Platelet survival in acute proliferative glomerulonephritis.

نویسندگان

  • J A Carruthers
  • I Ralfs
  • T M Gimlette
  • R Finn
چکیده

S U M M A R Y 1. Platelet survival was measured in patients with acute proliferative glomerulonephritis or chronic renal failure and also in control subjects. 2. Platelet survival is markedly reduced in acute proliferative glomerulonephritis as compared with control subjects; it was slightly reduced in patients in chronic renal failure due to interstitial renal disease and maintained on dialysis.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat.

We investigated whether platelet-derived growth factor (PDGF), or its receptor (PDGF-R), was upregulated in a rat model of mesangial proliferative glomerulonephritis. A marked increase in both PDGF A- and B-chain mRNA could be demonstrated in glomerular RNA by Northern blot analysis 3 and 5 days after disease induction, corresponding to the time of mesangial cell proliferation. PDGF-R beta-subu...

متن کامل

Extracapillary proliferative glomerulonephritis in Russell's viper bite.

Renal changes in snake bite include tubular necrosis, cortical necrosis, interstitial nephritis, arteritis, and thrombophlebitis.'-3 Glomerular changes are usually mild,' and severe glomerulonephritis is uncommon.4 We report the case of a patient bitten by a Russell's viper who presented with acute renal failure. A renal biopsy specimen showed extracapillary proliferative glomerulonephritis in ...

متن کامل

Bimodal effects of platelet-derived growth factor on rat mesangial cell proliferation and death, and the role of lysophosphatidic acid in cell survival.

Although mesangial cell death has been shown to be correlated with mesangial cell mitosis in vivo, little is known about how these two apparently opposite events are regulated. We show that the addition of platelet-derived growth factor (PDGF; 10-50 ng/ml) to primary cultured rat mesangial cells for 24 h caused continuous proliferation along with simultaneous cell death. This process was accomp...

متن کامل

C3 mesangial proliferative glomerulonephritis initially presenting with atypical hemolytic uremic syndrome: a case report

BACKGROUND Hemolytic uremic syndrome is characterized by acute renal failure, thrombocytopenia, and Coombs-negative hemolytic anemia. In C3 mesangial proliferative glomerulonephritis, an increase in mesangial cell proliferation without thickening in the glomerular capillary wall can be seen under light microscopy, but the definitive diagnosis is made with the immunohistologic demonstration of i...

متن کامل

A Rare Case of Castleman’s Disease of Plasma Cell Type Complicated with Membranoproliferative Glomerulonephritis

Castleman’s disease (CD) is an uncommon atypical lymphoproliferative disorder with different histological and clinical forms. Patients with the plasma cell type frequently present with systemic symptoms; including fever, weight loss, hemolytic anemia, hypoalbuminemia, hypergammaglobulinemia and increased acute-phase proteins. Renal manifestations like proteinuria or hematuria are common in Cast...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Clinical science and molecular medicine

دوره 47 5  شماره 

صفحات  -

تاریخ انتشار 1974